A local nonprofit biotech firm dedicated to finding treatments for ALS says it will use half of the $3 million it has received in donations in the past month to bring the second drug in its 15-year history to clinical trials two years earlier than it would have otherwise. The president and CEO of Cambridge-based […]

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MediciNova is set to begin a clinical trial of MN-166 (ibudilast) to treat patients with amyotrophic lateral sclerosis (ALS), following the approval from the US Food and Drug Administration (FDA). The randomized, double-blind, placebo-controlled trial is divided into two treatment arms, MN-166 and matching placebo, and includes a six-month treatment period followed by a six-month […]

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A series of studies begun by Harvard Stem Cell Institute (HSCI) scientists eight years ago has lead to a report published today that may be a major step forward in the quest to develop real treatments for amyotrophic lateral sclerosis, ALS, or Lou Gehrig’s disease. The findings by Harvard professor of Stem Cell and Regenerative […]

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NEW YORK (MarketWatch) — The ice bucket challenge has raised more than $40 million for ALS over the last two months, $8.6 million on Tuesday alone. But what does that really mean? Besides the millions of viral videos now circulating the web, there is an entire force of big pharmaceutical companies and non-profit clinics and […]

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Results from a meta-analysis of 11 independent amyotrophic lateral sclerosis (ALS) research studies are giving hope to the ALS community by showing, for the first time, that the fatal disease may be treatable. Researchers say progress in treating ALS, also known as Lou Gehrig’s disease, may be made by targeting new mechanisms revealed by neural […]

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I was faced with ALS for the first time at the age of 7, when I found out that my beloved teacher, Mr. Pendergast, had been diagnosed with the horrible disease. We were too young to really understand what to make of his news, but I did know that ALS meant Mr. P was sick […]

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Amyotrophic lateral sclerosis (ALS), often referred to as “Lou Gehrig’s Disease,” is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body. The progressive degeneration of the motor neurons in ALS […]

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